Structure of the human DNA repair geneHAP1and its localisation to chromosome 14q 11.2–12

Chromosome Duplication (14q) and The Genotype Phenotype Correlation

DNA repair fine structure and its relations to genomic instability.

It is timely to review aspects of DNA repair as there have recently been major advances in this field. These insights have provided information regarding new linkages between DNA repair defects and cancer. Several human repair genes have been identified and cloned, and a direct molecular connection has been established between DNA repair and transcription. The main focus of this review is to ex...

the underlying structure of language proficiency and the proficiency level

هدف از انجام این تخقیق بررسی رابطه احتمالی بین سطح مهارت زبان خارجی (foreign language proficiency) و ساختار مهارت زبان خارجی بود. تعداد 314 زبان آموز مونث و مذکر که عمدتا دانشجویان رشته های زبان انگلیسی در سطوح کارشناسی و کارشناسی ارشد بودند در این تحقیق شرکت کردند. از لحاظ سطح مهارت زبان خارجی شرکت کنندگان بسیار با هم متفاوت بودند، (75 نفر سطح پیشرفته، 113 نفر سطح متوسط، 126 سطح مقدماتی). کلا ...

The 14q+ chromosome in pre-B-ALL.

A child who had acute lymphoblastic leukemia (ALL) associated with an 8;14 chromosome translocation and with a pre-B phenotype is described. The leukemic cells were determined to be pre-B-cells on the basis of intracytoplasmic mu-chain immunoglobulin (cIgM+) and the common-ALL antigen, lack of receptors for sheep erythrocytes, and lack of surface immunoglobulin. The 8;14 translocation is freque...

Benign hereditary chorea of early onset maps to chromosome 14q.

Benign hereditary chorea (BHC) is an autosomal dominant disorder characterized by an early-onset nonprogressive chorea. The early onset and the benign course distinguishes BHC from the more common Huntington disease (HD). Previous studies on families with BHC have shown that BHC and HD are not allelic. We studied a large Dutch kindred with BHC and obtained strong evidence for linkage between th...